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Keep in mind that that the estrogen related side effects would occur mostly depending on the dose that you administer. Because of the fact that water retention as well as loss of muscle definition are common side effects with the higher doses of testosterone, this drug is most commonly considered to be a bad choice for dieting or during the cutting phases of training as people tend to lose the water retention and keep muscle definition during this period. Androgenic Side Effects of Testosterone Propionate It is a very well known fact that the elevated levels of testosterone are very likely to produce some androgenic side effects which is obvious taking in consideration that testosterone is the primary androgen hormone and most commonly, such side effects are including: oily skin, acne as well as body and facial hair growth. Due to the androgenic negative effects, those men that are having a genetic predisposition for hair loss androgenic alopecia also may notice that they are having accelerated male pattern balding by using the testosterone regardless of the ester. This side effect will Testosterone Gel 1% affect those men that are not predisposed to male pattern hair loss. Testosterone cream in bodybuilding usual virilizing side effects includes: menstrual irregularities, facial hair growth, a deepening of the voice, changes in the skin texture as well as clitoral enlargement. In addition to that, in the androgen responsive target tissues like for example prostate, skin and scalp, the high relative androgenicity of the testosterone is very dependent on its reduction to the dihydrotestosterone DHT, Androgel. The 5 alpha reductase enzyme is being responsible for that metabolism of testosterone. With this being said, it is important to know that using alongside with testosterone a product like dutasteride or finasteride which are 5 alpha reductase inhibitors are going to interefere with the site specific potentiation of testosterone action and this is going to lower the tendency of testosterone drugs to offer androgenic side effects. It is also very important to remember that both the anabolic as well as the androgenic effects are being mediated via the cytosolic androgen receptor. Hepatotoxicity Side Effects of Testosterone Propionate As it has been discovered, testosterone is having absolutely no hepatotoxic effects and for this reason, liver toxicity is very unlikely to happen while administering Testosterone Propionate.